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13 mar 2024 · Combining single-cell RNA-sequencing with high-resolution multiplexed error-robust fluorescence in situ hybridization reveals in detail the cellular interactions and specialization of cardiac...
Our results demonstrate that primitive MΦs enhance vascularized cardiac tissue performance via two primary mechanisms: direct cellular interaction and the release of matrix metalloproteinases (MMPs) alongside other pro-angiogenic and cardiac-related cytokines, resulting in long-term perfusable tissues with increased cellular viability and ...
28 wrz 2018 · Characterization of the progenitor cells that form the heart and of the gene regulatory networks that control their deployment is of major importance for understanding the origin of congenital...
24 wrz 2020 · Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease.
24 sie 2022 · SeisWind® 3D is an evolution of Fugro’s UUHR seismic service that consists of eight solid custom specification digital streamers, with proprietary sources and decimetre accuracy in-sea positioning systems.
scRNA-seq analysis revealed diverse cell lineages of the developing zebrafish heart. •. Molecular diversity of myocardial subpopulations suggests functional specializations. •. Novel role of pacemaker-enriched atp1b3b and colec10 in heart rate and morphogenesis. •. Single cell transcriptome profile of various cardiac cell types as valuable resource
This brief review will give a general overview of some major intracellular signalling systems operative in cells comprising the heart and vasculature, with particular emphasis on the pleiotropic roles of protein kinases as regulators of cell behaviour.
