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28 lut 2022 · Developing new platforms and technologies to assess the contractile functions of in vitro cardiac models is essential to provide information on cell/tissue physiologies, drug-induced...
28 lut 2022 · In this review, we described a variety of emerging approaches that have been developed to evaluate the contractile functions of in vitro cardiac models at the cellular and tissue levels. Platform designs, fabrication methods, sensing principles, cell types and model configurations have been described throughout this review.
14 cze 2023 · Introduction. The healthy contraction of the cardiac muscle is initiated by an action potential (AP) generated in the sinoatrial node (SA-node). From the SA-node, the AP propagates as an...
24 sie 2022 · SeisWind® 3D is designed to offer an efficient data acquisition footprint with the highest resolution to enable detailed ground modelling and interpretation of near surface geology for the safe development of offshore projects.
1 maj 2024 · Heart disease involves irreversible myocardial injury that leads to high morbidity and mortality rates. Numerous cell-based cardiac in vitro models have been proposed as complementary...
21 cze 2024 · Our results demonstrate that primitive MΦs enhance vascularized cardiac tissue performance via two primary mechanisms: direct cellular interaction and the release of matrix metalloproteinases (MMPs) alongside other pro-angiogenic and cardiac-related cytokines, resulting in long-term perfusable tissues with increased cellular viability and ...
We demonstrated that flow induction on the chip led to the formation and maturation of functional vessels from stem cell-derived endothelial cells. Upon applying oxidative stress to the vessels-on-chip, the early onset of cardiovascular disease was investigated.
