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29 kwi 2024 · Cell cycle regulation in mammalian cardiomyocytes involves the repression of cell cycle activators, such as cyclins, CDKs, and CDK-activating kinases (CAKs), along with CKIs . This leads to cardiomyocyte cell cycle arrest during cardiac development .
25 cze 2020 · Abstract. The formation of new blood vessels after myocardial infarction (MI) is essential for the survival of existing and regenerated cardiac tissue. However, the extent of endogenous...
28 sie 2017 · This review focuses on the cardiac cell cycle and its variants during postnatal growth, the different regenerative responses of the heart in dependance of the developmental stage and on manipulations of the cell cycle.
31 maj 2022 · We clearly identified the three major cell types of the cardiac vascular niche: fibroblasts (Dcn +, Col1a1 +, Pdgfrα +), endothelial cells (Kdr +, Pecam1 +), and mural cells (Rgs5 +, Kcnj8...
28 sie 2017 · This review focuses on the cardiac cell cycle and its variants during postnatal growth, the different regenerative responses of the heart in dependance of the developmental stage and on manipulations of the cell cycle.
24 wrz 2020 · Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease. Cardiovascular...
6 kwi 2021 · Here, we review both the classical and recent literature on the molecular and cellular mechanisms underlying heart regeneration, with a particular focus on how injury triggers the cell-cycle re-entry of quiescent cardiomyocytes to replenish their massive loss after myocardial infarction or ventricular resection.
