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Ketosis-prone diabetes (KPD) is an intermediate form of diabetes that has some characteristics of type 1 and some of type 2 diabetes. Type 1 diabetes involves autoimmune destruction of pancreatic beta cells which create insulin.
Ketone-prone diabetes or Flatbush diabetes is being increasingly recognized worldwide. It is typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality in the onset of age and gender variation is increasingly observed worldwide.
2 paź 2018 · Major questions remain as to its pathogenesis and whether it is a unique type of diabetes or a subset of more severe type 2 diabetes with greater loss of insulin action in target tissues. This review summarizes the main clinical and mechanistic studies to improve the understanding of ketosis-prone (Flatbush) diabetes.
Le diabète de type 2 prédisposé à la cétose/diabète atypique/diabète flatbush est un syndrome répandu, émergent et hétérogène caractérisé par des patients qui présentent une acidocétose diabétique (ACD) ou une cétose non provoquée avec hyperglycémie, mais qui n'ont pas nécessairement le phénotype typique du diabète de ...
In 2002, Sobngwi et al. introduced the term “ketosis-prone diabetes” in a review of diabetes in West Africans. Ketosis-prone diabetes, also known as “Flatbush Diabetes”, has pathophysiology close to that of T2DM but initially exhibits signs and symptoms of T1DM .
22 sie 2023 · Ketosis-prone diabetes (KPD) comprises a group of diabetes syndromes characterized by severe beta cell dysfunction (manifested by presentation with DKA or unprovoked ketosis) and a variable clinical course.
2 paź 2018 · This review summarizes the main clinical and mechanistic studies to improve the understanding of ketosis-prone (Flatbush) diabetes. Recent findings: Little data are available on the magnitude of KPD in the different susceptible populations.
