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  1. 3 sie 2019 · The document outlines the anatomy and physiology of neurons involved in nerve conduction and the mechanism of action of local anesthetics in blocking nerve conduction. It discusses pharmacokinetics including uptake, distribution, metabolism and excretion.

  2. 25 sty 2017 · This document provides information on local anesthesia. It begins with definitions and history, describing how local anesthesia was developed by Koller in 1884 using procaine. It then discusses the various methods of inducing local anesthesia and the neuroanatomy and electrophysiology of nerve conduction. The remainder of the document focuses ...

  3. 11 cze 2010 · - Local anesthetics are drugs that cause reversible loss of sensation, especially pain, in a localized area of the body when applied topically or injected locally. They block the generation and conduction of nerve impulses at the site of contact without damaging neurons.

  4. 7 sie 2014 · Pharmacology of Local Anesthetics Outline • History • Chemistry and Structure-Activity Relationships • Mechanism of Action • Pharmacological effects and toxicities • Clinical aspects.

  5. The Pharmacology of Local Anaesthetic Agents (LA) Local anaesthetic agents can be defined as drugs, which are used clinically to produce reversible loss of sensation in a circumscribed area of the body.

  6. Local_anesthetics.ppt - Free download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text File (.txt) or view presentation slides online. Local anesthetics work by reversibly blocking sodium channels and preventing the propagation of action potentials.

  7. “Eutectic Mixture of Local Anesthetics”: Mixture of lidocaine and prilocaine. Patch or cream. For children to reduce the pain of venipuncture, arterial cannulation, lumbar puncture, dental procedures, and skin graft donor site. TAC: Tetracaine + Adrenaline + Cocaine. For repair of minor lacerations.

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