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Enteroaggregative E. coli (EAEC) are a major cause of diarrhoea worldwide. Due to their heterogeneity and carriage in healthy individuals, identification of diagnostic virulence markers for pathogenic strains has been difficult.
In this review, we describe the clinical significance of EAEC regarding patterns of infection in humans, transmission, reservoirs, and symptoms. Manifestations associated with EAEC infection include watery diarrhea, mucoid diarrhea, low-grade fever, nausea, tenesmus, and borborygmi.
15 wrz 2020 · The role of enteropathogenic Escherichia coli (EPEC) as a cause of diarrhea in cancer and immunocompromised patients is controversial. Quantitation of fecal bacterial loads has been proposed as a method to differentiate colonized from truly infected patients.
7 gru 2009 · Several effector proteins that are secreted by the type III secretion system of enteropathogenic, enterohaemorrhagic and enteroinvasive E. coli have been shown to hijack and manipulate host cell...
4 maj 2020 · Enteroaggregative E. coli (EAEC) are emerging pathogens most commonly associated with acute and persistent paediatric diarrhoea and growth retardation in developing nations 1. In addition, EAEC...
Enteroaggregative Escherichia coli (EAEC or EAggEC) are a pathotype of Escherichia coli which cause acute and chronic diarrhea in both the developed and developing world. [1] [2] They may also cause urinary tract infections. [2]EAEC are defined by their "stacked-brick" pattern of adhesion to the human laryngeal epithelial cell line HEp-2. [3] The pathogenesis of EAEC involves the aggregation ...
10 lut 2023 · Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide, and its incidence is steadily rising in developing areas. Bacterial pathogens from the gut microbiota have been recognized as important risk factors for CRC. This review updates the current knowledge of Escherichia coli-produced genotoxins related to CRC.