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23 lis 2022 · IN JANUARY 2022, Bjornevik and colleagues published the results of a 20-year prospective seroepidemiologic study on the relationship between Epstein-Barr virus (EBV) and multiple sclerosis (MS) in which investigators observed an enormous increase in the risk of MS after EBV infection.
24 sty 2022 · Now, a study led by Stanford Medicine researchers has proved that the Epstein-Barr virus, a common type of herpes virus, triggers multiple sclerosis by priming the immune system to attack the body’s own nervous system.
The central role of Epstein-Barr virus in causing multiple sclerosis is examined to understand how it triggers the disease and presents new opportunities for treatment.
Role of Epstein-Barr virus in the development of MS EBV triggers MS by molecular mimicry, promoting memory B cells that function as pro-inflammatory antigen-presenting cells for T cells and by establishing a latent infection in B cells.
21 mar 2024 · The article provides an overview of the role of EBV in the pathogenesis of MS and makes a case for targeting EBV as a treatment strategy for MS. Recent findings: EBV potentially triggers autoimmunity via molecular mimicry or immune dysregulation.
11 mar 2022 · Epstein-Barr virus (EBV) is a putative trigger for multiple sclerosis (MS). Bjornevik et al. utilized longitudinal analysis of 10 million adults to strongly link MS to EBV infection1 and Lanz et al. identified clonally expanded B cells in MS that bind EBV EBNA1 and GlialCam.2
7 lut 2023 · Epstein-Barr virus antibodies in serum and DNA load in saliva are not associated with radiological or clinical disease activity in patients with early multiple sclerosis
