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1 lip 2024 · EPA’s draft risk evaluation preliminarily shows that chronic exposure to 1,1-dichloroethane contributes to the unreasonable risk to aquatic species, including invertebrates and algae, from the manufacturing, processing, and disposal of 1,1-dichloroethane.
Figure 2-13. 1,1-Dichloroethane Occupational Exposure Conceptual Model for Industrial and Commercial Activities and Uses: Worker and Occupational Non-User Exposures and Hazards.
Evaluation for 1,1-Dichloroethane (U.S. EPA, 2023a) describes some clarifications and different approaches that were implemented than those described in the 2021 Draft Systematic Review Protocol in response to (1) SACC comments, (2) public comments, or (3) to reflect chemical-specific risk evaluation needs. 2.1 Clarifications
breakdown of 1,1,1-trichloroethane, tetrachloroethylene, 1,1,2-trichoroethene, and 1,1-dichloroethane (ATSDR, 1994; IARC, 1999; and U.S. EPA, 1985 a, b). The chemical and physical properties of 1,1-DCE (ATSDR, 1994; IARC, 1999) are presented below. CAS name: 1,1-dichloroethene CAS number: 75-35-4 IUPAC name: 1,1-dichloroethylene
In short, the EPA document fails to identify many common conditions of use of 1,1-DCA, even though this information is publicly available from EPA and other government agencies. The following technical report is based on public information, including company literature and
EPA has classified ethylidene dichloride as a Group C, possible human carcinogen. Please Note: The main source of information for this fact sheet is the Agency for Toxic Substances and Disease Registry's (ATSDR's) Toxicological Profile for 1,1-Dichloroethane.
Technical grade 1,1-dichloroethane in corn oil was administered by gavage 5 days/week for 78 weeks to groups of 50 Osborne-Mendel rats/sex/dose. All surviving animals were necropsied following a 33-week observation period. Due to toxicity, dosing was not continuous (3 weeks on then 1 week off), making