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28 sty 2018 · Increasing knowledge of eosinophil biological behaviour is leading to major changes in established paradigms for the classification and diagnosis of several allergic and autoimmune diseases and has paved the way to a “golden age” of eosinophil-targeted agents.
The eosinophil is a leukocyte whose granules stain beautifully and avidly with the acidic red dye eosin (also known as bromoeosin, solvent red 43, 2′,4′,5′,7′-tetrabromofluorescein or C 20 H 8 Br 4 O 5). This cell, or a counterpart of this cell, exists in virtually all vertebrates (see Figure 1). 1 Even though its existence has only ...
27 wrz 2022 · Our understanding of eosinophil biology, development, and regulation has dramatically increased in the past decade, leading to new paradigms for the role of eosinophils in human health and disease and, perhaps more importantly, providing insights toward novel treatment strategies in the fight against eosinophil-mediated inflammation.
16 lis 2012 · This Review describes the unique biology of the eosinophil. The authors explain how eosinophils interact with other leukocyte populations to promote protective immunity following infection.
1 sty 2014 · This book consists of 26 chapters written by experts in the field of eosinophil biology that provide comprehensive and clearly written protocols for techniques designed to underpin research into the function of the eosinophil in health and disease.
11 wrz 2017 · Tissue-resident eosinophils selectively secrete cytokines and other mediators that have diverse functions in health and disease. Eosinophils are a prominent cell type in particular host...
28 sty 2018 · In this review, we provide a comprehensive update on the pathophysiological role of eosinophils in host defence, inflammation, and cancer and discuss potential clinical implications in light of recent therapeutic advances.
