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In patients admitted to the hospital with exacerbations of chronic obstructive pulmonary disease (COPD), eosinopenia is associated with increased mortality, increased rate of ventilation, and longer hospital stays. [2]
Eosinopenia is defined as an absolute eosinophil count of less than 0.09 × 10 9 /L and can be difficult to detect because the reference interval is low. Eosinopenia often accompanies other cytopenias in conditions that result in marrow hypoplasia, specifically involving leukocytes.
16 mar 2021 · Eosinophils are circulating and tissue-dwelling leukocytes that have been implicated in allergic respiratory pathology and antiviral host defense. While eosinopenia has been identified as a factor that may facilitate disease diagnosis and determine prognosis, this finding is neither definitive nor pathognomonic for COVID-19.
24 maj 2021 · Eosinopenia has been identified as a potential biomarker of sepsis in the past decade. However, its clinical application progress is slow and its recognition is low. Recent studies have again focused on the potential association between Eosinopenia and severe infections.
Eosinophil deficiency can be regarded as having several origins: first, as a spontaneous occurrence in human diseases; second, as a result of genetic manipulations in experimental animals; and third, as an effect of pharmacological agents specifically designed to reduce eosinophil numbers.
5 lut 2021 · Viral pneumonia is the most relevant clinical presentation of COVID-19 which may lead to severe acute respiratory syndrome and even death. Eosinopenia was often noticed in patients with COVID-19 pneumonia, but its role is poorly investigated.
8 lut 2021 · Eosinophils are multifunctional leukocytes implicated in the pathogenesis of several inflammatory processes including viral infections. We focus our study on the prognostic value of eosinopenia as a marker of disease severity and mortality in COVID-19 patients.
