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Eosinopenia is associated with several disease states and conditions, including inflammation and sepsis, endogenous catecholamines, and use of glucocorticoids. [1] There are also medications that deliberately target eosinophils in order to treat eosinophil-mediated diseases, causing drug-induced eosinopenia.
Eosinopenia is defined as an absolute eosinophil count of less than 0.09 × 10 9 /L and can be difficult to detect because the reference interval is low. Eosinopenia often accompanies other cytopenias in conditions that result in marrow hypoplasia, specifically involving leukocytes.
Eosinopenia, if progressively worsening, indicates that COVID-19 patients may progress to critical disease and have a significantly higher chance of mortality. Additionally, eosinopenia correlates with biomarkers of coagulation disorder and those of tissue damage in kidney, liver, and other tissues.
18 cze 2020 · This finding is particularly useful and helpful for patients triage at the time of an epidemic outbreak when large number of patients with COVID-19 or COVID-19-like symptoms are expecting confirmative nucleic acid tests and/or radiographic examination, while related resources are limited.
In the following sections, we will review the role of eosinophils in human health and disease at a general level and describe the evidence supporting eosinophilic immune dysfunction as a deleterious factor in chronic airway inflammation and in systemic inflammatory diseases.
24 maj 2021 · Eosinopenia has been identified as a potential biomarker of sepsis in the past decade. However, its clinical application progress is slow and its recognition is low. Recent studies have again focused on the potential association between Eosinopenia and severe infections.
Eosinopenia as Predictor of Disease Severity in Patients With Community-Acquired Pneumonia An Observational Study To the Editor: Lower respiratory tract infections, including community-acquired pneumonia (CAP), are a frequent cause of death worldwide.1 Aprevious study2 found that 38% of CAP patients requiring
