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The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the central nervous system (including the brain) and peripheral nervous system.
11 sie 2021 · Though recently discovered, the endocannabinoid system regulates and controls many of our critical bodily functions. Researchers are investigating the ECS's role in learning and memory and in hunger, hoping that these avenues of research may lead to new drug discoveries.
The basic functions of the ECS have were summarized in 1998 by Professor Di Marzo as, “relax, eat, sleep, forget and protect.” There are two primary endogenous cannabinoids, or endocannabinoids, arachidonylethanolamine (AEA), nicknamed anandamide from the Sanskrit word for “bliss,” and 2-arachidonylglycerol (2-AG). CB 1
18 lis 2004 · Endocannabinoids are released upon demand from lipid precursors in a receptor-dependent manner and serve as retrograde signalling messengers in GABAergic and glutamatergic synapses, as well as modulators of postsynaptic transmission, interacting with other neurotransmitters, including dopamine.
13 mar 2012 · Endocannabinoids (eCBs) are lipid mediators, isolated from brain and peripheral tissues that include amides, esters, and ethers of long chain polyunsaturated fatty acids; they mimic the action of Δ 9-tetrahydrocannabinol (THC) in different biological processes.
Current research suggests endocannabinoids may regulate the following functions: Appetite and digestion. Sleep. Pain sensation. Inflammation. Mood. Metabolism. Learning ang memory. Reproduction. May be a target for pathological functions such as: Parkinson’s. Huntington’s disease, Alzheimer’s. Multiple Sclerosis.
1 wrz 2004 · The components (Figs 3,4) and possible physiological functions of the endocannabinoid system have been extensively reviewed in recent articles 16,17 and will be outlined here only briefly ...
