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Jaundice is a yellow discoloration of the skin and eyes caused by hyperbilirubinemia (elevated serum bilirubin concentration).
When the total serum bilirubin (TSB) rises above the 95 th percentile for age (high-risk zone) during the first week of life, it will be considered as hyperbilirubinemia (4, 5). Between 60%–80% of healthy infants are expected to present with idiopathic neonatal jaundice (6).
6 lis 2019 · Neonatal jaundice is a clinical manifestation of elevated total serum bilirubin (TSB), termed neonatal hyperbilirubinemia, which results from bilirubin that is deposited into an infant's skin. The characteristic features of neonatal jaundice include yellowish skin, sclerae, and mucous membranes.
5 sie 2022 · Infants 7 days or older with a persistently elevated TSB within 2 mg/dL of the phototherapy threshold may have prolonged indirect hyperbilirubinemia, which can be confirmed by measuring serum direct-reacting or conjugated bilirubin (ie, a fractionated bilirubin measure) in addition to total bilirubin.
31 paź 2023 · This guideline covers diagnosing and treating jaundice, which is caused by increased levels of bilirubin in the blood, in newborn babies (neonates). It aims to help detect or prevent very high levels of bilirubin, which can be harmful if not treated.
Total serum bilirubin (SBR): unconjugated (indirect) and conjugated (direct), then FBE and Coombs depending on clinical presentation. Transcutaneous bilirubinometers (TCB) can be used as a screening tool to assess bilirubin levels from 24 hours – 2 weeks of age in near-term infants.
4 maj 2021 · International guidelines for the management of neonates with unconjugated hyperbilirubinemia include treatment thresholds that are based on total serum bilirubin (TSB) concentrations. Bilirubin...
