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2 mar 2016 · Prevention of drug poisoning is the best form of management. Always act sensibly with your dog’s medications: only give the prescribed dose and avoid giving anything that was designed for humans. Other safeguards include keeping medications in a locked cabinet, or on a high shelf which your dog cannot reach.
This lecture will briefly review pharmacology of NSAIDs, organ system dysfunction associated with toxicity, decontamination strategies for asymptomatic patients, and a review of traditional and novel therapies for NSAID intoxication.
If you suspect that your pet has ingested a prescription (or over-the-counter) NSAID, you should immediately contact your veterinarian or an animal poison control center. Treatment of NSAID poisoning consists of removing any drug that has not been absorbed, protecting the gastrointestinal tract and kidneys, and providing supportive care.
General Treatment of Poisoning. Immediate, life-saving measures may be needed initially. Beyond this, treatment consists of preventing further absorption of the poison, providing supportive treatment, and administering specific antidotes, if available.
Treatment consists of supportive care, including medication to control seizures. Vomiting can be induced if the exposure is recent and the animal is not yet showing signs. Comatose animals should be given intravenous fluids and treated for dangerously low body temperature.
Treatment: Exposures to illicit or abused drugs in pet animals can be accidental, intentional, or malicious. Occasionally, drug-sniffing dogs also ingest these substances. Because of the illegal nature of illicit or abused drugs, owners may provide inaccurate, incomplete, or misleading exposure histories.
Traditional management of non‐steroidal anti‐inflammatory drug (NSAID) intoxication includes gastrointestinal decontamination, intravenous administration of fluids (IVF), and gastroprotection. Intravenous administration of lipid emulsion (ILE) and therapeutic plasma exchange (TPE) are popular novel therapeutic strategies.
