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Drug excretion is the final step in the ADME (Absorption, Distribution, Metabolism, and Excretion) process and consists of a series of pathways that remove an administered drug and/or its metabolites from the body.
4 lip 2023 · Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well.
Drug excretion refers to the removal of drug from the body. Generally, only hydrophilic molecules are excreted effectively. Accordingly, drugs may be excreted as unchanged parent molecules if they are sufficiently hydrophilic.
1 sty 2022 · Definition. Drug excretion comprises those processes responsible of physically removing a drug, unchanged, from the body. Drug metabolites can also be excreted as well. The main routes for excretion are, undoubtedly, urinary excretion and biliary excretion.
1 gru 2018 · Drug excretion involves processes responsible of physically removing a drug from the body, either unchanged or in the form of biotransformation products. The main routes for drug excretion are the urine and the bile.
The biliary system contributes to excretion to the degree that drug is not reabsorbed from the gastrointestinal (GI) tract. Generally, the contribution of intestine, saliva, sweat, breast milk, and lungs to excretion is small, except for exhalation of volatile anesthetics.
Drug excretion is the removal of drugs from the body, either as a metabolite or unchanged drug. There are many different routes of excretion, including urine, bile, sweat, saliva, tears, milk, and stool. By far, the most important excretory organs are the kidney and liver.
