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1. www.aafp.org › pubs › afpDrug Dosing Adjustments in Patients with Chronic Kidney Disease -...

   www.aafp.org › pubs › afp

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   15 maj 2007 · Chronic kidney disease affects renal drug elimination and other pharmacokinetic processes involved in drug disposition (e.g., absorption, drug distribution, nonrenal clearance...

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2. www.ncbi.nlm.nih.gov › books › NBK560512Renal Failure Drug Dose Adjustments - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK560512

   27 lip 2024 · Renal disease primarily affects drug dosing in 3 ways: Patient susceptibility: Patients with renal impairment may be more vulnerable to a specific drug effect. Pharmacodynamic change: The effect of a drug may be increased or decreased in patients with renal disease.

3. www.ncbi.nlm.nih.gov › pmc › articlesDrug Therapies Affecting Renal Function: An Overview - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   26 lis 2021 · There is a wide range of side effects due to the multiple mechanisms of injury that drugs can have on the kidney. These side effects vary in severity [ 2 ]. Specifically, the incidence of drug-induced acute kidney injury (AKI) is 60% [ 3 ].

4. www.ncbi.nlm.nih.gov › pmc › articlesMedication Safety Principles and Practice in CKD - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   7 lis 2018 · In this review, we will present the key issues and threats to safe medication use in kidney disease, with a focus on predialysis CKD, as the scope of medication safety in ESKD and transplantation are unique and deserve their own consideration.

5. www.ajkd.org › article › S0272-6386(21)00625-9Principles of Kidney Pharmacotherapy for the Nephrologist: Core...

   www.ajkd.org › article › S0272-6386(21)00625-9

   16 lip 2021 · Patients with kidney disease carry an increased medication burden compared with patients with normal kidney function, with 80% of patients taking more than 5 medications per day. The prevalence of polypharmacy increases as chronic kidney disease (CKD) stage worsens and comorbidities increase.

6. www.kidney-international.org › article › S0085-2538(15)54984-3Drug dosing consideration in patients with acute and chronic...

   www.kidney-international.org › article › S0085-2538(15)54984-3

   Drug dosage adjustment for patients with acute or chronic kidney disease is an accepted standard of practice. The challenge is how to accurately estimate a patient’s kidney function in both acute and chronic kidney disease and determine the influence of renal replacement therapies on drug disposition.

7. kdigo.org › wp-content › uploadsDrug dosing consideration in patients with acute and chronic...

   kdigo.org › wp-content › uploads

   committee considered to be of central importance: (1) effects of impaired kidney function on drug disposition and response, (2) patient assessment for drug dosing, (3) calculating drug doses for patients with AKI and CKD, and (4) drug removal by intermittent and continuous renal replacement therapies. The breakout group deliberations were ...