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Digoxin loading oral: 500-750mcg 2 doses 6 hours apart (max 1500mcg in 24 hours) Maintenance dose. 62.5mcg – 250mcg daily. Note: when converting from the oral to the IV formulation the dosage should be reduced by 33% to take account of the difference in bioavailability.
21 sie 2023 · For maximal early benefits in treating tachyarrhythmias, digoxin requires loading doses, which can be administered intravenously or orally. Studies show that digoxin use is declining but is still prevalent.
This loading dose worksheet is intended to guide medical, nursing and pharmacy staff in the safe and appropriate prescribing and administration of intravenous digoxin loading doses in adult patients.
30 maj 2006 · For atrial fibrillation, a loading dose of 0.5 to 0.75 mg, followed by a maintenance dose, is warranted when the rate is not controlled with β-blockers. To achieve chronic optimal rate control, β-blocker dose rather than digoxin dose should be adjusted.
13 lip 2024 · DOSE. loading = 1mg in divided doses over 24 hrs; maintenance = 10-20mcg/kg/day; take level 12-24 hours post administration (take long time to distribute to heart) therapeutic range = 0.6-1.2nmol/L; if started in ICU only measure level @ 5-7 days; INDICATIONS. SVT (AF): 1-3ng/mL; Heart failure: 0.5-0.8ng/mL; Prevention of supraventricular ...
Loading dose – normal renal function: Digoxin oral (preferred route) 500micrograms followed 6 hours later by 500–1000micrograms in divided doses > 6 hours apart or Digoxin IV 500micrograms followed 6 hours later by 250–500micrograms in divided doses 4–6 hours apart.
Prescribe a loading dose of 250–750 micrograms a day for 7 days, followed by a maintenance dose. A clinical response is usually seen within one week. The BNF recommends a loading dose for rapid digitalisation of 750 micrograms to 1.5 mg in divided doses, dose to be given over 24 hours.
