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Here we present a 66-year-old female with both liver and renal dysfunction, who presented with severe digoxin toxicity despite mildly elevated serum levels. CASE PRESENTATION: Patient is a 66-year-old female with a history of end stage renal disease on hemodialysis, decompensated cirrhosis who presented to our hospital for altered mental status.
8 paź 2024 · The ECG features of digoxin effect are seen with therapeutic doses of digoxin and are due to: Shortening of the atrial and ventricular refractory periods — producing a short QT interval with secondary repolarisation abnormalities affecting the ST segments, T waves and U waves.
0% Complete. Digoxin ECG changes: arrhythmias, conduction defects and waveform changes. Digoxin may be used in patients with heart failure, atrial fibrillation, atrial flutter, and in selected cases of paroxysmal supraventricular tachycardia.
The diagnosis of digoxin toxicity is based primarily on clinical suspicion and clinical features (including ECG changes) suggestive of digoxin intoxication, and can be confirmed by assessment of serum digoxin levels.
Digoxin toxicity is characterised by gastrointestinal distress, hyperkalemia and life-threatening dysryhthmias, including increased automaticity and AV nodal blockade; Digoxin has a narrow therapeutic index and chronic toxicity is more likely in the elderly and those with renal impairment
19 sty 2023 · The kidneys excrete digoxin in direct proportion to the glomerular filtration rate; the liver metabolizes 16%. Digoxin has a half-life that varies from 36 to 48 hours, which may increase in cases of renal failure.
8 paź 2024 · Digoxin toxicity ECG changes with dysrhythmias. Review of EKG features of digoxin toxicity and cardiotoxicity with example EKG
