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  1. 25 lip 2018 · They identified a significant increase in harmful side effects, such as personality changes, confusion and sedation, related to the use of commonly prescribed opioid painkillers in people with dementia, compared to those on a placebo.

  2. This systematic review of the literature identified a total of 16 meta-analyses that evaluated the use of antipsychotics in individuals with dementia. Overall, 12 meta-analyses evaluated the efficacy of antipsychotics among individuals with dementia. Of these, eight also assessed adverse effects.

  3. 14 gru 2022 · Risks related to antipsychotic use in dementia are moderated by a number of modifiable and non-modifiable factors such as co-prescribing of other medications, medical and psychiatric co-morbidities, and demographics such as age and sex, making individualised treatment decisions challenging.

  4. Side-effects of medication. In older people, antipsychotics must be used with particular caution because of the side-effect profile, including extrapyramidal symptoms, sedation, anticholinergic effects including increased confusion, cardiovascular effects and tardive dyskinesia. See the BNF and MHRA website for further information.

  5. 27 lip 2021 · The main concerns are anticholinergic and extrapyramidal side effects, parkinsonism, sedation, falls and increased mortality in patients with dementia; fewer extrapyramidal side effects when atypical neuroleptics are used; possible alternatives are neuroleptics of low potency (e.g. melperone, pipamperone) or atypical neuroleptics with a ...

  6. 1 paź 2012 · Several factors may increase the risk of drug-induced cognition disorders in elderly persons; these include imbalances in neurotransmitters (e.g., acetylcholine), age-related alterations in pharmacokinetics and pharmacodynamics, and high levels of medication use.

  7. The most common side effects of donepezil, rivastigmine and galantamine are: loss of appetite. feeling sick (nausea) diarrhoea or vomiting. headaches. feeling tired or dizzy. difficulty sleeping well. When to see a doctor. If these side effects are concerning or do not go away after a few weeks, it’s important to talk to the doctor or pharmacist.

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