Search results
1 sie 2010 · Biological clocks act through hormones to control the pace of aging. Recent studies confirm that aging is hormonally regulated and that the evolutionarily conserved insulin/IGF-1 signaling (IIS) pathway plays a key role in the hormonal regulation of aging.
- PubMed
Despite recent advances in molecular biology and genetics,...
- PubMed
1 paź 2010 · Despite recent advances in molecular biology and genetics, the mysteries that control human lifespan are yet to be unraveled. Many theories, which fall into two main categories: programmed and error theories, have been proposed to explain the process of aging, but neither of them appears to be fully …
16 gru 2022 · Aging is a ubiquitous biological process that results in a progressive and irreversible decline in physical function across all organ systems that is induced by the accumulation of damage in...
1 lis 2015 · In roundworms, genetic mutations that double the lifespan provide clear evidence that genes influence aging and longevity. However, no single identified gene completely controls aging, consistent with the concept that the genetic control of aging is multifactorial.
1 lis 2015 · This article will explore several common theories about why and how we age. By understanding current aging theories, clinicians can follow advances in aging research and intelligently address patient questions about life extension therapies and strategies to slow aging.
30 wrz 2024 · However, at the biological level, numerous mechanisms interact with each other and the environment, producing unique signatures of aging in each individual . At the clinical level, numerous pathologies interact, with variable consequences for health and the priorities of the patient, and rarely with any clear etiological target.
19 sty 2024 · This Review explores mechanistic theories of aging, discusses challenges in establishing causality of these mechanisms and suggests that genetically informed investigation will help address...
