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13 mar 2023 · Cold urticaria is a chronic condition causing episodic symptoms of cold-induced wheals or angioedema in response to direct or indirect exposure to cold temperatures. Whereas symptoms of cold urticaria are typically benign and self-limiting, severe systemic anaphylactic reactions are possible.
8 lis 2023 · Cold urticaria is characterized by pruritic wheals (hives) and/or angioedema due to cutaneous mast cell degranulation and their release of proinflammatory mediators after cold exposure of the skin. Triggers include skin contact with cold objects, cold liquids, and cold air.
Cold urticaria, or cold contact urticaria, is a subtype of physical urticaria . The physical urticarias are forms of inducible urticaria, in which there is a specific and definite stimulus that triggers the development of symptoms.
Our systematic review included 16 studies, 9 of which met the eligibility criteria for the meta-analysis. We analyzed the effects of treatments on critical temperature thresholds (CTTs) and critical stimulation time thresholds (CSTTs), as well as on rates of complete response and adverse events.
MANAGEMENT OF COLD URTICARIA SYNDROMES. The decision to treat cold urticaria syndromes depends primarily on the underlying etiology, severity of response to cold stimulus, and how greatly it affects quality of life, including the frequency of anticipated cold exposure.
Cold urticaria is a hypersensitivity to cold exposure (eg, wind, freezer compartments, cold water) resulting in histamine release. It usually presents as localized redness, burning, pruritus, and urticaria in the exposed areas, but may progress to a generalized systemic reaction, shock, and death.
This treatment pathway provides an evidence-based approach for the treatment of urticaria whilst maximising cost effectiveness and clinical outcome for use by all healthcare professionals involved in patient care.
