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  1. 26 wrz 2018 · Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the presence of one or more cold shock domains. In humans, the best characterized members of this family are denoted Y-box binding proteins, such as Y-box binding protein-1 (YB-1).

  2. 22 lip 2016 · Function of Cold Shock Proteins During Cold Shock. Csps have a highly conserved nucleic acid binding domain, called the cold shock domain (CSD) (Graumann and Marahiel, 1996). CSD contains two nucleic acid binding motifs, ribonucleoprotein 1 and 2 (Lee et al., 2013) that facilitate binding to target RNA and DNA (Chaikam and Karlson, 2010).

  3. Cold shock proteins are fascinating molecular entities that exhibit a unique structural composition, enabling them to perform their functions effectively. These proteins are typically small, with a highly conserved domain known as the cold shock domain (CSD).

  4. 22 lut 2014 · The presence of cold shock domain proteins in the blood and/or urine of patients with cancer or inflammatory disease, as well as the identification of autoantibodies directed against these proteins make them potential targets of therapeutic interest.

  5. 14 sty 2015 · RBM3 is an RNA-binding cold-shock protein produced in the brain in response to cooling, but its function in synaptic plasticity is unknown. Giovanna Mallucci and colleagues show that...

  6. Cold Shock Proteins (CSPs) are protective proteins produced under cold conditions to mitigate the damage or harmful effects at membranes and undesirable RNA structures that impede translation initiation and elongation [80].

  7. This review summarizes the features of cold shock domain (CSD) proteins in the context of their interactions with nucleic acids and describes similarities and differences in the structure of cold shock proteins of prokaryotes and CSD proteins of eukaryotes with special emphasis on the functions rela ….

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