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  1. 15 sie 2013 · Cold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment.

  2. As a result, in many cases cold agglutinin disease is not diagnosed correctly for months or even years. If you suspect that your patient has cold agglutinin disease, ask the patient to go to a testing center where a sample can be drawn and processed immediately under warm conditions.

  3. 11 mar 2021 · The last decades have seen great progress in the treatment of cold agglutinin disease (CAD). Comparative trials are lacking, and recommendations must be based mainly on nonrandomized trials and will be influenced by personal experience.

  4. 2 gru 2016 · Primary chronic cold agglutinin disease (CAD) is a well-defined clinicopathologic entity in which a specific, clonal lymphoproliferative B-cell bone marrow disorder results in autoimmune hemolytic anemia.

  5. 16 wrz 2022 · Enjaymo is now Approved. Introducing ENJAYMO–the first and only approved treatment in Cold Agglutinin Disease (CAD). ENJAYMO is a prescription medicine used to decrease the need for red blood cell transfusion due to the breakdown of red blood cells (hemolysis) in adults with CAD. Find out more.

  6. 26 cze 2024 · Cold agglutinin disease (CAD) is a form of autoimmune hemolytic anemia (AIHA) in which cold agglutinins (IgM autoantibodies against red blood cell [RBC] antigens that bind at cold temperatures) can cause clinical symptoms related to RBC agglutination in cooler parts of the body and hemolytic anemia.

  7. 9 kwi 2019 · Cold agglutinin disease (CAD) is a complement-dependent, classical pathway-mediated immune hemolytic disease, accounting for 15–25% of autoimmune hemolytic anemia, and at the same time, a distinct clonal B-cell lymphoproliferative disorder of the bone marrow.

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