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Four studies indicated that positive associations are dependent on age. These studies reported positive associations between caffeine consumption and dementia and/or cognitive function at older ages (65–74 years versus 35–64 years , >70 years versus <70 years , 90 years versus 70 years ).
As far as a beneficial effect of coffee is concerned, a large multicenter cohort study from three European countries (Holland, Finland, Italy) in elderly men demonstrated that coffee consumption was associated with slower progression of dementia, measured over the course of 10 years.
1 mar 2015 · Among diet-associated factors, coffee is regularly consumed by millions of people around the world and owing to its caffeine content, it is the best known psychoactive stimulant resulting in heightened alertness and arousal and improvement of cognitive performance.
1 kwi 2014 · These findings were echoed in a recent study by Liu and colleagues who found that coffee consumption of more than 4 cups/day was associated with increased all-cause mortality for men and women under 55 years of age, but not for older adults (72).
10 cze 2022 · Caffeine, a key psychoactive ingredient in coffee, is a short-acting neurostimulator with known neuromodulator effects on the brain by inhibiting phosphodiesterase, mobilizing intracellular calcium, antagonism of adenosine receptors, and modulation of GABA receptor function [15].
5 mar 2015 · Among diet-associated factors, coffee is regularly consumed by millions of people around the world and owing to its caffeine content, it is the best known psychoactive stimulant resulting in heightened alertness and arousal and improvement of cognitive performance.
Recent epidemiological evidence suggests that coffee consumption reduces the risk of cognitive decline, dementia, and AD. Eskelinen et al. (2009) reported a 65 % risk reduction for late-life dementia and AD among drinkers of three to five cups of coffee per day during their middle life, compared with nondrinkers.
