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  1. Study with Quizlet and memorize flashcards containing terms like Structure of a B-cell receptor, True or False: Antigen binding to BCR does *not* depend on APC processing; the BCR binds "native" epitopes, whether discontinuous or linear, peptide or carbohydrate, BCR is a monomer of _____ and more.

  2. In clonal selection of B cells, which substance is responsible for determining which cells will eventually become cloned? a. antibody b. antigen c. interferon d. complement

  3. Study with Quizlet and memorize flashcards containing terms like adaptive defenses--> humoral immunity, primary response, activated B cells and more.

  4. During clonal selection, random mutations during clonal expansion cause the production of B cells with increased antibody-binding affinity for their antigens. The clonal selection hypothesis may explain why secondary immune responses are so effective at preventing reinfection by the same pathogen.

  5. B Cells Make Antibodies as Both Cell-Surface Receptors and Secreted Molecules. As predicted by the clonal selection theory, all antibody molecules made by an individual B cell have the same antigen-binding site. The first antibodies made by a newly formed B cell are not secreted.

  6. 15 maj 2022 · The above figure illustrates the activation of the one B cell in a pool of B cells whose BCR is specific for an epitope (small dark spheres) on the antigen. This phenomenon is called clonal selection because it is antigen that selects particular lymphocytes for clonal expansion.

  7. 31 sie 2023 · Animation Overview: Clonal Selection and Clonal Expansion. During its development, each B-lymphocyte becomes genetically programmed, through a process called gene translocation, to make a unique antibody molecule that will function as a B-cell receptor.

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