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  1. antibiotics licensed for the prophylaxis of UTIs are trimethoprim and nitrofurantoin. The risk of adverse effects (see box below), as well as common side-effects such as rashes, oral/vaginal thrush, and gastrointestinal upset, should be discussed with the patient.

  2. 11 maj 2021 · Ciprofloxacin* 250-750 mg po BID 400 mg IV q12 hr Uncomplicated Cystitis: 250 mg po BID Uncomplicated Pyelonephritis: 500 mg po BID * Dose adjustment needed based on renal function **Dose depends on disease state (Uncomplicated UTI, Complicated UTI, Pyelonephritis),

  3. • Review antibiotic prophylaxis for recurrent UTI at least every 6 months. • Patients who have urine cultures confirming resistance to the prophylactic agent they are on, should have their prophylaxis stopped (exposure to antibiotic without benefit) and a clinical

  4. The objective of the guidelines panel was to provide evidence-based guidance on the diagnosis, treatment, and prevention of urinary tract infections (UTIs) and male accessory-gland infections, while addressing crucial public health aspects related to infection control and antimicrobial stewardship. Methods.

  5. Continuous antibiotic prophylaxis is effective in reducing UTI frequency in CISC users with recurrent UTIs, and it is well tolerated in these individuals. However, increased resistance of urinary bacteria is a concern that requires surveillance if prophylaxis is started.

  6. Prophylactic measures against recurrent uncomplicated UTI. Conservative measures including limiting spermicide use and postcoital voiding lack evidence for their efficacy but are unlikely to be harmful (Level 4 evidence, Grade C recommendation).

  7. A number of fluoroquinolones, including ciprofloxacin, have been shown to be effective in 3-day regimens for the treatment of AUC in women; several trials have suggested that single-dose regimens of fluoroquinolones are effective in the treatment of AUC; however, these regi-mens are not as effective as 3-day regimens [9].

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