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Each chromosome has a distinct banding pattern, and each band is numbered to help identify a particular region of a chromosome. This method of mapping a gene to a particular band of the chromosome is called cytogenetic mapping. For example, the hemoglobin beta gene (HBB) is found on chromosome 11p15.4.
Figure 1 shows an overview of the chromosome 11 landscape. HSA11 is very gene rich and there are many clustered gene families located on the chromosome. According to a recent survey of...
The 11th human chromosome is one of the most gene-rich and disease-rich chromosomes in the human genome (70, 71). Though it needs to be further investigated, our studies revealed a novel...
Two copies of chromosome 11, one copy inherited from each parent, form one of the pairs. Chromosome 11 spans about 135 million DNA building blocks (base pairs) and represents between 4 and 4.5 percent of the total DNA in cells. Identifying the genes on each chromosome is an active area of genetic research.
biomaRt R package example 3: What Ensembl genes are in a 100,000 base pair region of chromosome 11 surrounding HBB? What chromosome band are they on, what strand, and what type of genes are they?
The physical map, high-quality finished sequence and gene catalogue presented here are but the latest landmark in an effort to understand the unique characteristics and functions of this chromosome. The clone map and finished sequence Chromosome 11 was sequenced using a clone-by-clone shotgun sequencing approach.
Idiograms provide a pictorial reference point that is useful for locating the positions of individual genes on chromosomes, as well as for identifying various abnormalities associated with a...
