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  1. At about 21.5 genes per megabase, chromosome 11 is one of the most gene-rich, and disease-rich, chromosomes in the human genome. More than 40% of the 856 olfactory receptor genes in the human genome are located in 28 single-gene and multi-gene clusters along the chromosome.

  2. 23 mar 2006 · HSA11 is very gene rich and there are many clustered gene families located on the chromosome. According to a recent survey of the Ensembl genome browser 8, HSA11 contains the fourth highest...

  3. Researchers have identified genes on the short arm of chromosome 11 that are associated with particular features of WAGR syndrome. A loss of the PAX6 gene disrupts normal eye development, leading to aniridia and other eye problems, and may also affect the development of the brain.

  4. 23 mar 2006 · Initial gene annotation indicates an average gene density of 11.6 genes per megabase, including 1,524 protein-coding genes, some of which were identified using novel methods, and 765 pseudogenes. One-quarter of the protein-coding genes shows overlap with other genes.

  5. 3 wrz 2023 · It has been found that genetic changes in chromosome 11, including deletions and rearrangements, play a role in the development of neuroblastoma. Ewing sarcoma : Ewing sarcoma is a rare type of bone cancer.

  6. 21 lip 2013 · Chromosome 11 contains about 40% the estimated 1,000 genes for olfactory receptors in the human genome.

  7. Chromosome 11 is singular in that it carries hosts of genes involved in various illnesses. At least 180 genes involved in perceiving smells are found on the chromosome.