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In the new era of genetic profiling of tumors and targeted therapeutics, this review describes the epidemiology, pathology, molecular characteristics, and current management with ongoing clinical trials for chRCC.
21 lut 2019 · A renal tumour core biopsy provides histopathological con-firmation of malignancy with high sensitivity and specificity; it is especially recommended before treatment with ablative therapies [III, B] as well as in patients with metastatic disease before start-ing systemic treatment [III, B].
13 sie 2021 · Chromophobe renal cell carcinoma (chRCC) appearing as a small incidental renal mass in a 53-year-old man. Axial noncontrast (a) , nephrographic phase (b) , and excretory phase (c) CT images show a small solid renal mass (arrow) with enhancement less than that of the renal parenchyma.
1 gru 2021 · Chromophobe renal cell carcinoma (ChRCC) is the third most common renal cell carcinoma (RCC) subtype, which predominantly occurs in sporadic setting. ChRCCs are considered to originate from the intercalated cell of distal tubules with two main morphological variants, classic and eosinophilic.
14 sie 2023 · Chromophobe renal cell carcinoma (ChRCC) is the second most common variant histology (non-clear cell) RCC. ChRCC is distinct from clear cell RCC (ccRCC) in terms of genetics, genomics, metabolism, cell of origin, and response to targeted and immune therapies. The pathogenesis of ChRCC remains unclear, but current data suggest two potential ...
Pathologic analysis reveals only moderate vascularity. The most common imaging pattern is a predominantly solid renal mass with circumscribed margins and enhancement less than that of the renal cortex. The authors discuss chRCC with emphasis on correlative pathologic findings and illustrate the multimodality imaging appearances of chRCC by ...
30 wrz 2018 · Chromophobe renal cell carcinoma (ChRCC) makes up approximately 5% of all cases of renal cell carcinoma (RCC) . First described in 1985, this rare subtype of RCC was originally thought to arise from the intercalated cells of the collecting ducts.
