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Charles River uses the IGS program to manage production of the Crl:CD1(ICR) mouse. The IGS program is a management system used to minimize inbreeding and manage random genetic drift that would otherwise lead to colony divergence among colonies bred in different locations worldwide.
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- Outbred Mice Datasheet
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- Transgenic Model Creation Services
Generating Genetically Engineered Mice and Rats for...
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- CD1-Elite
Routine Health Monitoring of Isolator-Reared VAF/Elite ®...
- Cell & Gene Therapy CDMO Solutions
Charles River, a cell and gene therapy CDMO solutions...
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Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.
Charles River is a global supplier of mouse models, including genetically standard, disease-specific as well as surgically altered mice, for biomedical research.
Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The CD-1® Heterozygous mouse is the control for the CD-1® Nude Mouse.
CD-1® IGS Mouse. The original group of Swiss mice that served as progenitors of CD-1 mice consisted of two male and seven female albino mice derived from a non-inbred stock in the laboratory of Dr. de Coulon, Centre Anticancereux Romand, Lausanne, Switzerland.
Routine Health Monitoring of Isolator-Reared VAF/Elite ® Animals. Charles River breeds laboratory mice, such as the CD1-Elite mouse, for use in basic research and nonclinical drug discovery and development.
Uncover the versatility of ICR (CD-1 ®) mice in biomedical research: ICR (CD-1 ®) Mice: The Versatile Workhorses of Biomedical Research. Characteristics: Coat: Albino; Docile disposition; Excellent reproductive and maternal characteristics; High incidence of retinal degeneration (Pde6b rd1) Litter average: 11.5; Most widely-used outbred mouse
