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In our systematic review, we identified the most recent and significant national and international guidelines and compared their recommendations. We also underlined the most apparent differences among these guidelines to identify ‘hot topics’ on CD and possible future developments.
Currently, the only treatment for celiac disease is a life-long, strict gluten-free diet leading to improvement in quality of life, ameliorating symptoms, and preventing the occurrence of refractory celiac disease, ulcerative jejunoileitis, and small intestinal adenocarcinoma and lymphoma.
1 lut 2023 · Celiac disease can be defined as a condition in which there is an abnormal small intestinal mucosa that improves morphologically when treated with a gluten-free diet and relapses when gluten is reintroduced.
18 sty 2023 · The following eight recommendations are outlined in this summary: Using upper gastrointestinal endoscopy with multiple duodenal biopsies for confirming the presence of the disease in both children and adults.
Both serology and biopsy should be performed on a gluten-containing diet. The treatment for celiac disease is primarily a gluten-free diet (GFD), which requires significant patient education, motivation, and follow-up. Non-responsive celiac disease occurs frequently, particularly in those diagnosed in adulthood.
Drug discovery for treating CD, as a complement to a GFD, aims to intervene in different scenarios, including (a) maintenance therapy, (b) rescue therapy after acute gluten exposure, and (c) the mitigation of inadvertent chronic gluten exposure [15].
20 lis 2020 · Currently, the only accepted treatment for coeliac disease is a strict, life-long gluten-free diet (GFD), which usually results in the alleviation of symptoms and in improvement of...
