Search results
The CD-1 mouse is a multipurpose research animal model that can be used in such fields as toxicology (safety and efficacy testing), aging and oncology.
- Careers
Find your moment to make a significant impact on global...
- Outbred Mice Datasheet
CD-1® IGS Mouse* Nomenclature: Crl:CD1(ICR) Strain Code: 022...
- Email Us
Chętnie wyświetlilibyśmy opis, ale witryna, którą oglądasz,...
- Place an Order
Chętnie wyświetlilibyśmy opis, ale witryna, którą oglądasz,...
- Careers
Mouse CD1 binds peptides with a sequence motif comprising aromatic, bulky and hydrophobic amino acids with an overhanging NH 2 -terminus. The majority of these long peptides include aromatic residues at positions 1 and 7 and an aliphatic residue in position 4.
Studies using CD1d tetramers and CD1d-deficient mice provide important insight into the immunological functions of invariant NK T cells (iNKT) during viral and bacterial infections. However, the mouse CD1 locus is atypical because it encodes only CD1d, whereas most mammalian species have retained many CD1 genes.
3 sie 2023 · We have identified millions of previously unidentified CD-1 variants with the potential to confound studies involving CD-1. We used the identified variants to construct a CD-1-specific reference genome, which can improve accuracy and reduce bias when aligning genomics data derived from CD-1 mice.
Genetic Management of CD-1® IGS Mouse Colony. Charles River uses our IGS program to manage production of the Crl:CD1(ICR) mouse. The IGS program is a management system used to minimize inbreeding and manage random genetic drift that would otherwise lead to colony divergence among colonies bred in different locations worldwide.
5 gru 2022 · We used the identified variants to construct a CD-1-specific reference genome, which can improve accuracy and reduce bias when aligning genomics data derived from CD-1 individuals.
CD-1 IGS mice are outbred mice derived from a group of outbred Swiss mice developed at the Anti-Cancer Center in Lausanne, Switzerland. They were imported to the US in 1926 and to Charles River in 1959. The CD-1 IGS mice are generally used for genetics, toxicology, pharmacology, and aging research.
