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14 gru 2021 · Proteinuria can result from urinary tract infections, urinary stones, and other causes of postrenal inflammation; therefore, a UPCR should not be performed in dogs with an active urine sediment or urolithiasis.
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Renal proteinuria. Proteinuria of renal origin results from two major mechanisms. Glomerular disease causes a loss of selective filtration that results in an increased amount of protein in the filtrate. Glomerular disease is present in about 50% of dogs with CKD, but it is rare in cats.
Ensure that all secondary causes of proteinuria, such as infectious diseases, hyperadrenocorticism, disseminated malignancies and immune disorders have been considered and excluded or treated. Glomerular disease (UPC > 3) is estimated to account for 50% of chronic kidney disease in dogs.
22 paź 2021 · Chronic causes of proteinuria, such as inflammatory bowel disease, Cushing’s disease, or diabetes mellitus, may require long-term treatment. During treatment, your vet will try to stabilize the disease and prevent long-term kidney damage.
Treatment goals include decreasing the magnitude of proteinuria to the reference range to minimize progressive kidney damage, as well as preventing and treating the secondary consequences of the protein loss (e.g., thromboembolism).
4 dni temu · Less commonly persistent proteinuria can be caused by increased circulating levels of low molecular weight proteins. This article reviews mechanisms of proteinuria in dogs and cats and discusses the importance of screening for and ultimately treating proteinuria.
Treatment of proteinuria should be primarily directed against the origin of the disease causing the glomerular damage; further steps should be directed to control, if possible, the mechanisms that are at the base of the glomerular damage development.
