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  1. 14 mar 2023 · The available data suggest that high MPV is related to better survival in renal cancer (two out of two studies), bladder cancer (one out of one study), and multiple myeloma (one out of one study) (see the “Results” section). The relation between cancer and MPV is bidirectional and is analyzed below (Figure 2).

  2. Most studies in gastric, breast, endometrium, thyroid, and lung cancer documented an elevated MPV in cancer patients. Data were less clear-cut for esophageal, ovarian, and colon cancer, while reduced MPV was observed in renal cell carcinoma and gallbladder cancer.

  3. 17 kwi 2019 · A study conducted by Karagöz et al. showed a higher platelet count in colorectal cancer patients as compared to healthy subjects and lack of differences in MPV between the study group and control. Moreover, no changes were noted in MPV between patients with and without colorectal cancer metastases.

  4. 26 lut 2021 · Changes in mean platelet volume (MPV) have been demonstrated in cardiovascular disease, cerebrovascular disease, peripheral artery disease, Crohn’s disease, and colitis [79–83]. In addition, from studies by us and others, it is becoming increasingly clear that MPV is also affected during malignant diseases [23, 84–87].

  5. 19 lip 2022 · Conditions associated with high MPV results include: Cancer. Diabetes. Cardiovascular disease. Preeclampsia. Crohn’s disease. Hyperthyroidism. Immune thrombocytopenia. Myeloproliferative disease. Vitamin B12, D or folate deficiency. Macrothrombocytopenia (giant platelet disorders). What does it mean if your MPV blood test results are low?

  6. 14 mar 2023 · The role of MPV has been extensively investigated in several types of cancer, such as gastric, colon, breast, and lung cancer, while few data exist for other types, such as renal, gallbladder cancer, and multiple myeloma. Most studies in gastric, breast, endometrium, thyroid, and lung cancer documented an elevated MPV in cancer patients.

  7. 11 sty 2022 · Our study findings suggest that individuals with a high platelet count might be candidates for investigation for the presence of an occult cancer after other nonmalignant causes of an elevated platelet count have been ruled out.

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