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Pemphigus foliaceus (PF) is the most common autoimmune skin disease in dogs and cats. It is also the most common variant of pemphigus diseases,1,2 which are characterized by autoantibodies that target keratinocyte desmosomal proteins, leading to loss of cell-to-cell adhesion (acantholysis).
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Steps to the diagnosis of Pemphigus Foliaceus; Presentation and treatment difference between dogs and cats; Medication recommendations, including practical dosing and timeline schedules; What to do with refractory cases
Pemphigus foliaceus (PF), the most common form of pemphigus, also carries a relatively good prognosis, though the individual response to treatment can vary. Some dogs with PF achieve rapid control of clinical signs with medication and then can be gradually weaned off medication completely.
Pemphigus foliaceus (PF) is the most common autoimmune skin condition in dogs and cats. Here's how to diagnose PF at a patient’s initial presentation.
Treatment Options. Immunosuppressive therapy is used to treat pemphigus foliaceus. In dogs, the treatment of choice is oral glucocorticoid with or without concurrent steroid-sparing therapies such as azathioprine, chlorambucil, ciclosporin and mycophenolate mofetil.
The treatment for a pemphigus foliaceus dog is immune system suppression paired with topical creams and antibiotics. CBD for dogs helps manage health and wellness and boosts dogs' immune systems. Dogs with pemphigus foliaceus must have limited sun exposure.
