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  1. 6 sty 2022 · Excessive exercise, particularly with the use of eccentric contractions (often demonstrated using methods such as downhill running) have been shown to increase pro-inflammatory cytokines in the serum, within the muscle tissue itself, and within articular cartilage [102, 103].

  2. 29 maj 2024 · A detailed understanding of the tissue-specific downstream effects of exerkines is crucial to harness the health-related benefits mediated by exercise and improve targeted exercise programs in...

  3. 14 sie 2018 · Recent studies have revealed a finely tuned regulatory network that orchestrates skeletal muscle mitochondrial biogenesis and function in response to exercise and in disease states.

  4. 26 lut 2019 · The typical beneficial effects of exercise include lower body weight, better control of hypertension, glucose tolerance, decreased LDL cholesterol level, and an overall reduction in the risk...

  5. This review will highlight how exercise reduces metabolic disease risk by activating metabolic changes in non-skeletal-muscle tissues. We provide an overview of exercise-induced adaptations within each tissue and discuss emerging work on the exercise-induced integration of inter-tissue communication by a variety of signalling molecules ...

  6. 5 sty 2024 · Over time, the associated metabolic stress of each individual exercise bout provides the basis for long-term adaptations across tissues, including the cardiovascular system, skeletal muscle, adipose tissue, liver, pancreas, gut, and brain.

  7. 27 kwi 2018 · Muscle inflammation and loss of peripheral nerve functions cause muscle atrophy, replacement of skeletal muscle with adipose and fibrotic tissue, and a decrease of regenerative muscle capacity, or sarcasthenia.