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15 maj 2024 · Bubonic plague is the most common primary manifestation, with a bubo usually occurring in the groin, axilla, or cervical nodes. Buboes are often so painful that patients are generally guarded and have restricted movement in the affected region.
A rapid diagnostic test (RDT) could help prompt diagnosis of plague, especially in low-resource settings. This would improve patient care and help appropriate response to avoid the disease spread.
To assess the effect of forms of plague (bubonic, septicaemic, or pneumonic), specimen tested (bubonic aspirate, urine, or sputum), prior antibiotic treatment, location where the test is performed (field or laboratory studies), and threshold for detecting the disease (as set by the manufacturer) on the accuracy of the F1RDT for detecting the ...
F1RDT appears to be highly sensitive for pneumonic or bubonic plague. As a simple test that can be performed at a patient's bedside in remote and low‐resource areas, F1RDT can assist with plague diagnosis for early management, and appropriate preventive measures to avoid spread of the disease.
The test is simple to perform and provides a result within 15 minutes. It can be performed in the pus contained in the buboes (swellings), or in the sputum (mucous coughed up from the respiratory tract) of people with suspected pneumonic plague.
17 cze 2024 · Rapid recognition of the classic symptoms of this disease and laboratory confirmation are essential to instituting lifesaving therapy. Expertise in testing for plague bacilli is limited to...
18 sty 2003 · Our RDT is a specific, sensitive, and reliable test that can easily be done by health workers at the patient's bedside, for the rapid diagnosis of pneumonic and bubonic plague. This test will be of key importance for the control of plague in endemic countries.