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Higher plasma betaine concentrations of pregnant women at 26–28 weeks of gestation is associated with smaller infant birth size and lower abdominal fat mass of their offspring . Generally, maternal betaine supplementation normalizes fetal growth and adiposity of progeny of obese mice by reducing glucose and fatty acid transporters and the ...
24 maj 2018 · This study examines whether supplementation of betaine, a choline derivative, has positive effects on fetal metabolic outcomes in mouse progeny exposed to maternal obesity and GDM.
5 sie 2024 · Betaine is an important component of a healthy pregnancy. Getting enough betaine when you’re pregnant, either through diet or a prenatal vitamin, can ensure that you’re safeguarding your own health and that of your developing baby. Betaine is not the only nutrient needed for a healthy pregnancy.
24 maj 2018 · Calorie control and weight management during pregnancy do not consistently normalize fetal weight 23–27. Betaine has the potential to influence nutrient transport and epigenetic regulation of fetal genes, which may subsequently normalize fetal growth and metabolism.
3 cze 2021 · We aimed to investigate the associations between choline, betaine, methionine, dimethylglycine (DMG), trimethylamine N-oxide (TMAO) and GDM risk among women with twin gestations. Patients and methods: This hospital-based cohort study included 187 women with dichorionic twin gestations.
Maternal one-carbon metabolism during pregnancy is crucial for fetal development and programming by DNA methylation. However, evidence on one-carbon biomarkers other than folate is lacking. We, therefore, investigated whether maternal plasma methyl donors, that is, choline, betaine and methionine, are associated with birth outcomes.
This review discusses the roles of critical nutrients in pregnancy and the available evidence on the use of supplements to reduce risks and improve maternal and fetal outcomes. Recommendations are made for pregnant women, taking into account safety data and tolerable upper intakes set for pregnant women.
