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Beta-2-glycoprotein I (B2GPI) binds anionic phospholipids and is considered to be the predominant antigen in APS and antibodies against B2GPI (anti-B2GPI) are recognised in the laboratory criteria for APS diagnosis.
- The role of beta-2-glycoprotein I in health and disease associating ...
Beta-2-Glycoprotein I (β2GPI) plays a number of essential...
- A systematic review of the association between anti-β-2 glycoprotein I ...
Anti-β-2 glycoprotein I antibodies (anti-B2GPI) are often...
- The role of beta-2-glycoprotein I in health and disease associating ...
14 paź 2021 · Anti-beta 2 glycoprotein I antibodies in a general obstetric population: preliminary results on the prevalence and correlation with pregnancy outcome. Anti-beta2 glycoprotein I antibodies are associated with some obstetrical complications, mainly preeclampsia-eclampsia.
12 lip 2012 · Infection-related anti-β 2 GPI antibodies circulate for a short period of time. The increased risk of thrombosis of patients with persistently present anti-β 2 GPI antibodies can be explained in part by the circulation time of the autoantibodies.
Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that possess the dual capability to up and down regulate the complement and coagulation systems depending upon external stimulus.
Abstract. Anti-β (2)-glycoprotein I (anti-β (2)GPI) antibodies are the main antiphospholipid antibodies, along with anticardiolipin and lupus anticoagulant, that characterize the autoimmune disease antiphospholipid syndrome (APS).
1 sie 2019 · Recent advances allow us to propose antibodies targeting beta-2-glycoprotein I (β 2 -GPI) as the most specific antibodies associated with anti-phospholipid syndrome (APS). Therefore, there is now a crucial need for powerful biological assays to adequately monitor them.
26 paź 2021 · Anti-β-2 glycoprotein I antibodies (anti-B2GPI) are often cited as the major pathogenically relevant antibody in antiphospholipid syndrome (APS), but it is unclear if there is clinical evidence to support this theory. We performed a systematic review to determine if immunoglobulin G anti-B2GPI posit …