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Mahler M., Albesa R., Zohoury N., Bertolaccini M.L., Ateka-Barrutia O., Rodriguez-Garcia J.L. Autoantibodies to domain 1 of beta 2 glycoprotein I determined using a novel chemiluminescence immunoassay demonstrate association with thrombosis in patients with antiphospholipid syndrome.
In addition to a history of at least one clinical event, antiphospholipid syndrome classification criteria (table 1) require the stable presence of one or more of the following autoantibodies: anticardiolipin antibodies, aβ 2 GPI, or a lupus anticoagulant.
6 maj 2024 · Objectives: Identify the signs and symptoms of a patient with antiphospholipid syndrome. Apply best practices in the evaluation of antiphospholipid syndrome. Implement evidence-based treatment and management strategies for antiphospholipid syndrome depending on the clinical picture and results of laboratory testing.
1 lis 2023 · These antibodies are generally detected by three tests, namely: lupus anticoagulant (LA), anticardiolipin antibody (aCL), and anti-Beta-2-glycoprotein-I antibody (aβ 2 GPI). All of these create enhanced risk for blood clotting.
15 kwi 2020 · The risk of sepsis in patients with cancer has been estimated to be 10 times higher than that in patients without cancer, with considerable variations among cancer subtypes . Hematological malignancies, especially acute leukemia and myeloma, exhibit the highest risk of sepsis .
28 maj 2024 · Over 700 studies investigating immunotherapy in patients with sepsis have been performed and despite this body of evidence, the 2021 surviving sepsis campaign guidelines only include intravenous hydrocortisone as an immunomodulatory treatment for patients with vasopressor refractory septic shock . Perhaps patient stratification might be the way ...
30 mar 2021 · Therefore, while awaiting the results of well-designed randomized clinical trials, we advocate the inclusion of short-course aminoglycoside therapy with a BLA for IEAT when treating neutropenic cancer patients in centers with a high prevalence of multidrug resistance, especially if sepsis or septic shock are present.