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Patients treated with topiramate lost an average of 5.34 kg (95% confidence interval [95%CI] -6.12 to -4.56) of additional weight as compared with placebo. According to meta-regression analy-sis, treatment duration and dosage were associated with the efficacy of topiramate treatment.
27 kwi 2011 · To identify the potential effect of topiramate on clinically significant weight loss (weight loss ≥5% and ≥10%) as well as the effect of topiramate in causing adverse events, an overall odds ratio (OR) was calculated.
Topiramate may be a useful adjunctive treatment for obesity, and may play a role in the treatment of obesity in individuals with type 2 diabetes mellitus. Although warnings about some side effects were required for prescribing topiramate, the treatment was not associated with major harmful events.
26 lut 2024 · Side Effects . Topamax can cause a range of side effects. One important note is that your prescriber should take a baseline serum bicarbonate blood level before starting you on Topamax, as the drug can affect acid-base levels. This measurement is available as part of an electrolyte or metabolic lab panel.
31 sie 2023 · For all patients, three months correlated to stronger reductions in caloric intake p= 0.02, and at one year, weight loss correlated stronger to those with a higher BMI (p= 0.0007). The results confirmed that topiramate caused significant weight loss and was sustainable for one year with treatment.
13 mar 2024 · Common side effects when Topamax is used for weight loss are abnormal skin sensations (e.g., burning, tingling, numbness), altered sense of taste, and slowed thinking and movements. Other notable side effects include: Memory and concentration problems. Feeling nervous. Mood changes. Dry mouth. Changes in vision. Nausea. Dizziness. Fatigue
23 kwi 2024 · In these studies, the individual weight loss response to topiramate was highly variable as seen by the fact that all reporting standard deviations showed these to be as great or greater than mean weight loss values (13 – 18).
