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containing dioxin-like compounds (DLCs). 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and DLCs are structurally and toxicologically related halogenated aromatic hydrocarbons. The EPA recommends that the toxicity equivalence factor (TEF) methodology, a component mixture
20 lut 2024 · EPA will use TEQs to account for how dioxin and dioxin-like compounds vary in toxicity. TEQs will help the public to better understand the toxicity of releases and waste management at facilities that report under the Toxics Release Inventory Program.
The “Toxic Equivalent” (TEQ) scheme weighs the toxicity of the less toxic compounds as fractions of the toxicity of the most toxic TCDD. Each compound is attributed a specific “Toxic Equivalency Factor” (TEF) .
1 sty 2023 · As a notorious compound in the family of dioxins, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exhibits long-term toxic effects on diverse organs, which induces continuous metabolic disorders. This review discussed the mechanisms of TCDD-associated metabolic syndrome.
Sufficient toxicological data are now available to permit use of conventional risk assessment techniques to estimate the hazards associated with human exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin (2,3,7,8-TCDD).
1 maj 1991 · Toxicity equivalent factors (TEFs) have proved useful in estimating the toxicity of complex mixtures of chlorinated dibenzo-p-dioxins and dibenzofurans (CDDs/CDFs). An international consensus has formed around a specific set of TEF values as interim solution for addressing environmental contaminatio …
Based on data from the animal studies underlying the exposure guidance values, a serum lipid-adjusted dioxin toxicity equivalent (TEQ) concentration of approximately 15 ppt is consistent with the ATSDR minimal risk level (MRL) for dioxins.
