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  1. Antimicrobial Dosing Guideline. Purpose. This guideline is to be used in conjunction with Sheffield Children’s NHS Foundation Antimicrobial Formulary to aid the clinician in prescribing the most appropriate antimicrobial(s) at the appropriate dose. Intended Audience.

  2. 2.4 g (3 to 4 MU) IV 4-hourly (child: 150-200 mg/kg/day in 6-hourly doses). Alternatives include vancomycin (if likely urine or abdominal source, severe penicillin allergy, or any cephalosporin allergy) or ceftriaxone 2 g IV 12-hourly (child: 50 mg/kg up to 2 g 12-hourly).

  3. Children being discharged from ED or paediatric short stay ward with moderate CAP can be treated with a 3 day course of antibiotics (based on the CAP-IT study). For children being discharged from hospital following an admission due to CAP, 5 days total Ab course (3 days if. azithromycin).

  4. 31 sty 2021 · Antibiotics are very commonly prescribed for children presenting with uncomplicated lower respiratory tract infections (LRTIs), but there is little evidence from randomised controlled trials of the effectiveness of antibiotics, both overall or among key clinical subgroups.

  5. in children ≥ 6 months of age with non-severe signs or symptoms (i.e., mild otalgia for less than 48 hours and < 39°C [102.2°F], no otorrhea); initiate antibiotic therapy if the child worsens or fails to improve within 48 to 72 hours of symptoms onset. 1st line when antibiotic therapy indicated: Amoxicillin (high dose

  6. 27 mar 2023 · This document provides dosing recommendations that pertain to the majority of pediatric patients receiving care at UN hildren’s Hospital. The dosing regimens below are applicable to patients with normal renal function. As some antimicrobials have a range of dosing recommendations for those with

  7. The doses provided are general recommendations and do NOT include neonatal dosing, cystic fibro-sis dosing, or renal dose adjustment. Please refer to the Housestaf Manual (HSM) or Neofax for additional recommendations and indi-cation-specific dosing. Maximum individual doses in parentheses.

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