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Factor II (FII) deficiency (also called hypoprothrombinemia or prothrombin deficiency) is a rare coagulation disorder. People affected by this deficiency and those close to them have very little written information about it. This booklet explains the causes of FII deficiency, its symptoms and available treatments.
Factor II deficiency is very rare. Doctors estimate that it only affects about one in every two million people. What causes factor II deficiency? Factor II deficiency is an inherited genetic disorder. It is what is known as recessive, meaning you must inherit the gene defect from both parents. It affects men and women equally and can be found ...
Prothrombin (also known as factor II, or FII) deficiency remains one of the rarest coagulation disorders of the rare bleeding disorders (RBDs).
11 lip 2024 · A variety of inherited coagulation disorders are associated with clinical bleeding, including inherited deficiencies of factors XIII (13), XI (11), X (10), VII (7), V (5), and II (2, prothrombin), as well as some rare combined factor deficiencies.
10 sie 2021 · Rare coagulation factor deficiencies, more commonly referred to as rare bleeding disorders (RBD), comprise a rare group of disorders that can result in a variety of bleeding symptoms. Abnormalities in clotting times and low plasma factor activity levels help guide the diagnosis of factor II, V, VII, and X deficiencies.
Understanding Factor II deficiency (Prothrombin deficiency), a rare bleeding disorder. Learn about the symptoms, genetics, and treatment options.
30 cze 2015 · The STAT1/2 dimer protein complex binds to IRF9 in the nucleus and the resulting trimer interacts with DNA at transcription factor binding sites, and upregulates gene expression. The dotted red line indicates effects of STAT2 on mitochondrial fission, mediated by DRP1 phosphorylation in healthy cells.
