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23 sty 2024 · The regenerative mechanism of survival and replacement by iPSC-derived cartilage organoids contributes to defect healing independent of host progenitor cells and thus, does not require an invasive procedure like microfracture surgery.
27 paź 2020 · Repair and resurfacing of damaged joint cartilage is a major public health priority for this millennium. Articular cartilage is susceptible to blunt and cumulative trauma as well as...
1 gru 2022 · Here, we describe the current concepts for articular cartilage regeneration, highlighting the key actors of this process trying to identify the best perspectives. Discover the world's...
Injury to articular cartilage is recognized as a cause of significant musculoskeletal morbidity. The unique and complex structure of articular cartilage makes treatment and repair or restoration of the defects challenging for the patient, the surgeon, and the physical therapist. The preservation of articular cartilage is highly dependent on
Articular cartilage can be damaged by injury or normal wear and tear. Restoring articular cartilage can relieve pain and allow better function. Most important, it can delay or prevent the onset of arthritis .
A variety of treatments has the potential to improve healing of articular surfaces, including perforation of subchondral bone, altered joint loading, periosteal and perichondrial grafts, cell transplantation, growth factors, and artificial matrices.
Introduction. The numerous experimental and clinical attempts that have been made to induce the healing of histologic and macroscopic lesions within mature articular cartilage aim at re-establishing a structurally and functionally competent repair tissue of an enduring nature.
