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19 sie 2022 · The contemporary pharmaceutical industry is voicing growing concerns about the translatability and reproducibility of animal models. In addition, the usefulness of certain of the required regulatory safety tests in animals is being increasingly questioned.
21 paź 2020 · Two well-known examples clearly demonstrate why it is necessary to test drugs on animals before human trials are started. In 1937, an American company launched a product called “Elixir Sulfanilamide,” containing sulfanilamide dissolved in diethylene glycol (DEG) and flavored with raspberry.
This article reviews the use of non-human animals in biomedical research from a historical viewpoint, providing an insight into the most relevant social and moral issues on this topic across time, as well as to how the current paradigm for ethically ...
1 lut 2002 · This article will review how public concerns about animal experimentation developed, the recent activities of animal-rights groups, and the opportunities and challenges facing the scientific...
10 lip 2020 · Based on the authors’ experiences over the past 30 years in designing and supervising animal experiments, comprehensive guidelines for planning animal studies have been constructed, called PREPARE (Planning Research and Experimental Procedures on Animals: Recommendations for Excellence) .
Gale offers an overview of issues related to animal experimentation, derived from scholarly sources and academic journals. Read about legislation and activism.
5 kwi 2017 · A comparison between the ARRIVE and PREPARE checklists may also be found there. The PREPARE guidelines cover 15 main topics as shown in Table 1. The guidance in this paper should be adapted to the individual research project, animal species and loca-tion.
