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4 lip 2024 · Acute disseminated encephalomyelitis (ADEM), as the name would suggest, is featured by a monophasic acute inflammation and demyelination of white matter typically following a recent (1-2 weeks prior) viral infection or vaccination 4,6.
The patient's mother reported a history of sore throat and rhinorrhea in the past few days. Multiple T2/FLAIR hypersignal white matter lesions with the appropriate clinical history led to the diagnosis of ADEM.
This case demonstrates typical imaging features of ADEM, which although characterized as a monophasic illness, individual lesions are not all at the same stage of evolution, thus some small or inapparent lesions early on can be seen to appear and mature even while other lesions regress.
23 cze 2024 · Acute Disseminated Encephalomyelitis (ADEM) is an immune-mediated inflammatory disorder of the central nervous system, typically following a viral infection or vaccination. It is characterised by widespread demyelination, primarily affecting the white matter of the brain and spinal cord.
ADEM tylko sporadycznie występuje w powiązaniu z ospą wietrzną. Choroba zaczyna się prawie udarowo, często pojawiają się drgawki, i to zwykle w 2-8 dni od pierwszych objawów ospy wietrznej. Do wyjątków należy późniejsze pojawienie się ADEM.
8 cze 2022 · Background: Acute disseminated encephalomyelitis (ADEM) is a rare demyelinating disorder that is often misdiagnosed. To improve early diagnosis, we performed a systematic review and meta-analysis of clinical features, outcomes for ADEM in adults.
8 maj 2018 · Appearance of new lesions at MRI suggests the diagnosis of multiphasic ADEM or multiple sclerosis (MS). Diagnosis of acute disseminated encephalomyelitis is based on clinical and radiological features because there is no specific biological marker or confirmatory test.