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18 kwi 2024 · Acetaminophen (N-acetyl-para-aminophenol, paracetamol, APAP) toxicity is a common and potentially life-threatening condition due to its widespread availability and perceived safety. More than...
8 paź 2021 · Acetaminophen toxicity. October 8, 2021 by Josh Farkas. CONTENTS. Rapid Review. Epidemiology & pharmacokinetics. Clinical evolution. Patient evaluation. Decontamination. Who needs treatment? Acetylcysteine. Massive acetaminophen poisoning. Management of established hepatic failure. Management of renal failure. Podcast. Questions & discussion.
9 cze 2023 · Objectives: Review the pathophysiology of acetaminophen toxicity. Describe the four clinical stages of acetaminophen toxicity. Identify the treatment strategies for an alert patient who presents within an hour of overdose versus a patient who presents after two hours.
3 maj 2024 · Acetaminophen (N-acetyl-para-aminophenol, paracetamol, APAP) toxicity is a common and potentially life-threatening condition due to its widespread availability and perceived safety. More than...
13 sie 2024 · The pathophysiology, clinical manifestations, and diagnosis of acetaminophen toxicity in adults will be reviewed here. Treatment of this condition and evaluation of poisoning in children are discussed separately.
The use of paracetamol in children requires special care and maintain in an adequate dosage (based on age), which significantly differs from standard adult. The recommended dosage for children consider the metabolism of paracetamol, which determines the toxicity of the drug, especially hepatotoxicity (see below).
Acute, single, unintentional ingestion of acetaminophen: 1) Any patient with signs consistent with acetaminophen poisoning (e.g., repeated vomit-ing, abdominal tenderness in the right upper quadrant or mental sta- *Guidelines for the Management of Poisoning.