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  1. INSTRUCTIONS. Select the opiate and route that you wish to convert from. Input the total daily dose in milligrams of the opiate you are converting from. Select the opiate you wish to convert to. The total daily dose will be displayed in the results bar. When to Use. Pearls/Pitfalls.

  2. Equianalgesic conversions used in this calculator are based on the American Pain Society guidelines and critical review papers regarding equianalgesic dosing. 4, 5, 6, 7 When possible, chronic-dosing studies have been used, including bidirectional and dose-dependent conversions.

  3. The calculator provides conversions from one opioid to another and/or from one route of administration to another, to be used as a guide only. It is not tailored to any specific pain syndrome or for utilisation by specific healthcare professionals.

  4. Morphine Milligram Equivalents (MME) Calculator. Calculates total daily morphine milligram equivalents. IMPORTANT. There is no completely safe opioid dose, and this calculator does not substitute for clinical judgment. Use caution when prescribing opioids at any dosage, and prescribe the lowest effective dose.

  5. Purpose of Oral Morphine Equivalence (OME) calculations. OME calculations help identify opioid tolerance in individual patients. The FDA defines an opioid-tolerant patient as receiving for 1 week or longer at least 60 mg oral morphine/day or an equianalgesic dose of another opioid.

  6. opioid conversion calculators. • Identify the mathematical disparities in conversion. • Compare automated conversions against manual calculations. • Reveal potential risks to the end user.

  7. Listed below are methods for common conversions using standard published conversion ratios. The examples assume a change in drug or route at a time of stable pain control using equianalgesic doses. See Fast Fact #2 about conversions involving transdermal fentanyl; #75 and #86 about methadone.

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