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Select the opiate and route that you wish to convert from. Input the total daily dose in milligrams of the opiate you are converting from. Select the opiate you wish to convert to. The total daily dose will be displayed in the results bar.
Bidirectional conversions: When converting between certain opioids, the direction of conversion (eg, morphine to hydromorphone versus hydromorphone to morphine) will produce a different conversion ratio.
Morphine Milligram Equivalents (MME) Calculator. Calculates total daily morphine milligram equivalents. IMPORTANT. There is no completely safe opioid dose, and this calculator does not substitute for clinical judgment. Use caution when prescribing opioids at any dosage, and prescribe the lowest effective dose.
All conversions are made by first calculating the oral morphine equivalent daily dose (oMEDD) of the opioid being converted from, and then calculating the specific dose of the opioid being converted to.
OME calculations help identify opioid tolerance in individual patients. The FDA defines an opioid-tolerant patient as receiving for 1 week or longer at least 60 mg oral morphine/day or an equianalgesic dose of another opioid.
Step 1: Calculate current total daily usage of opioids. Morphine 30 mg /dose x 6 doses/day = 180mg/day. Step 2: Calculate the equipotent dose (consult conversion table).
The equianalgesic chart indicates that 1.5 mg of parenteral hydromorphone equals 7.5 mg of oral hydromorphone (a 5-fold increase). The patient’s current dose of 5 mg per day of parenteral hydromorphone is equal to 25 mg per day of oral hydromorphone.
